To mitigate the persistence of microplastics in the water, we aimed to improve the design of Ideonella sakaiensis, hoping to increase its growth rate and the rate for producing the plastic-disintegrating enzyme, Polyethylene terephthalate (PET). We looked at increasing the performance of its ATP-stimulated translocation promoter, changing the oxygen carrying capacity (Vitreoscilla hemoglobin (VHb)), altering its chemical environment and adjusting the environment temperature.